i have no personal experience

but talking to a couple of people who have been given them it seems  women are affectd more by them

a neighbour was prescribed them while in hosp after surgery,  she felt  really terrible and was nauseous , a sister so so annoyed by them having been prescribed she gave the doc a big telling off

the 2 men i know one takes them reg and seems a bit dopey sometimes, but he does take lots of meds

the other uses them as and when his bak plays up,  he has a dodgy tummy but says they do help him relax